17 Celebrity Co-Star Friendships That Give Great Friendship Goals

Hollywood is often perceived as a fiercely competitive environment, but when co-stars form real-life friendships that transcend the industry’s cutthroat nature, it’s truly something special. These bonds, forged on-screen and carried into reality, add depth to the characters we love and remind us of the genuine connections behind the glitz and glamour.

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Whether they met while filming or their camaraderie blossomed off-camera, these celebrity duos and groups are the epitome of friendship goals. From Sophie Turner and Maisie Williams’ “Stark Sisterhood” to Matthew McConaughey and Woody Harrelson’s “Friendship Tours,” these relationships inspire admiration and joy.

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Here are 17 iconic Hollywood friendships that prove real-life bonds can be as captivating as their on-screen counterparts:

1- Michelle Williams and Busy Philipps

Michelle Williams and Busy Philipps forged their incredible bond while working together on Dawson’s Creek at the start of their acting careers.

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Over the years, their friendship has grown stronger, and the two have been each other’s unwavering support systems. Busy has often accompanied Michelle to major award ceremonies, proudly standing by her side during significant moments.

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Philipps’ heartfelt Instagram tribute in 2020 showcased their deep connection: “I’m eternally grateful that we met all those years ago because there’s no one I’d rather weather all the storms with.”

2- Courteney Cox and Jennifer Aniston

From co-stars on the legendary sitcom Friends to lifelong confidantes, Courteney Cox and Jennifer Aniston are a shining example of enduring friendship.

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After the show’s conclusion in 2004, the pair remained inseparable, consistently celebrating each other’s successes and supporting one another through life’s highs and lows. Aniston, who is the proud godmother to Cox’s daughter Coco, often shares heartfelt tributes to her best friend on social media.

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In 2024, Jennifer penned a loving birthday message for Courteney, calling her “powerful, magical, mystical, and ferociously talented.” She concluded with, “It’s one of my great honors to call her one of my best friends for life.”

3- Drew Barrymore and Cameron Diaz

Since sharing the screen in the early 2000s for the Charlie’s Angels films, Drew Barrymore and Cameron Diaz have cultivated an unbreakable friendship.

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Their bond goes beyond professional camaraderie, with the two often sharing humorous and heartfelt moments that delight fans.

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Barrymore, in her typically candid style, once declared on her talk show, “I want to talk about body fluids for the rest of our lives and kick each other’s butts in every big and small moment that life has to offer.”

4- Tina Fey and Amy Poehler

Tina Fey and Amy Poehler’s friendship began long before their Saturday Night Live days, starting with their improv training in Chicago.

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Their shared sense of humor and quick wit helped them establish a lasting bond, which only deepened as they co-hosted the Golden Globes multiple times and collaborated on various projects. Fey describes their dynamic as one of ease and mutual understanding, saying, “We have a shorthand when working together.”

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Over the years, they’ve celebrated each other’s successes and supported one another’s creative ventures.

5- Ben Affleck and Matt Damon

Ben Affleck and Matt Damon have been friends since their childhood in Boston, a bond that only strengthened as they pursued their acting dreams together.

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Their journey to fame began with co-writing and starring in Good Will Hunting, a project that earned them an Academy Award. Over the years, the duo has continued collaborating on films like Dogma, Air, and The Last Duel.

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Beyond their professional success, Affleck and Damon have been each other’s pillars of support during challenging times.

Matt has credited Ben with helping him navigate the pressures of fame, calling their friendship “stabilizing.” Ben, in turn, has expressed gratitude for their lifelong connection, saying, “It’s been an enormous gift to be part of Matt’s life.”

6- Meghan Markle and Abigail Spencer

Meghan Markle and Abigail Spencer share a friendship that began even before their time on Suits.

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Their first meeting occurred during an audition in 2007, where Spencer immediately felt a connection with Meghan. Spencer described the moment as instant and undeniable, saying, “There was just something between us.”

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Their bond only deepened during their time on Suits, and they have remained close ever since. Abigail often speaks warmly of Meghan’s kindness, strength, and compassion, traits that have made her an incredible friend.

7- Taraji P. Henson and Mary J. Blige

The friendship between Taraji P. Henson and Mary J. Blige blossomed after they collaborated on Tyler Perry’s I Can Do Bad All By Myself in 2009.

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Since then, the two have been inseparable, often seen vacationing together and publicly praising each other’s accomplishments. Their mutual admiration is rooted in authenticity, as Blige once wrote, “Taraji is a real woman—fearless, authentic, and unapologetically herself.”

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Henson has similarly expressed her admiration for Blige’s talent and unwavering support. The pair often attend each other’s milestone events, with Mary speaking at Taraji’s Hollywood Walk of Fame induction and Taraji presenting an award to Mary at the Billboard Women in Music event.

8- Jenna Fischer and Angela Kinsey

Jenna Fischer and Angela Kinsey, who co-starred as Pam and Angela on The Office, share a friendship that transcended their time on the show.

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Their bond grew stronger over the years, with Kinsey describing Jenna as her “life anchor” and someone who provides clarity and peace. In 2019, they launched their hit podcast, Office Ladies, where they share behind-the-scenes stories and insights about their time on the beloved sitcom.

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Their collaboration extended further in 2021 when they co-authored Office BFFs: Tales of The Office from Two Best Friends Who Were There. Their friendship is a testament to their genuine care for each other, as they navigate both professional and personal challenges together.

9- Mindy Kaling and B.J. Novak

Mindy Kaling and B.J. Novak’s friendship began in 2004 when they joined the writers’ room for The Office.

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Over the years, their bond has been a mix of friendship, collaboration, and deep admiration for each other’s talents. While the two briefly dated, they ultimately decided they were better as best friends.

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Novak has been a constant presence in Kaling’s life, even serving as the godfather to her children. In his speech at the 2023 Norman Lear Awards, Novak praised Kaling for her unwavering passion, integrity, and creativity.

10- Salma Hayek and Penélope Cruz

Salma Hayek and Penélope Cruz share a sisterly bond that began when Cruz first arrived in Los Angeles to pursue her acting career.

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Hayek immediately took Cruz under her wing, helping her navigate the complexities of Hollywood. Over the years, their friendship has only grown stronger as they supported each other through various stages of life—dating, marriage, and motherhood.

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Hayek credits their friendship with helping them endure the challenges of the industry, calling Cruz family.

11- America Ferrera, Amber Tamblyn, Blake Lively, and Alexis Bledel

The stars of The Sisterhood of the Traveling Pants—America Ferrera, Amber Tamblyn, Blake Lively, and Alexis Bledel—formed a deep bond during their time filming the beloved movie.

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Over the years, their friendship has stood the test of time, with the four supporting each other’s personal and professional milestones. Whether it’s showing up to cheer on Ferrera during her Barbie premiere or standing by Lively during her legal battles.

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Their unwavering support highlights the strength of their connection. Ferrera has often spoken about how much the group means to her, calling them her “sisters for life.”

12- Kristen Wiig and Maya Rudolph

Kristen Wiig and Maya Rudolph’s friendship began during their time on Saturday Night Live, and it blossomed as they continued to collaborate on projects like Bridesmaids.

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Rudolph once described working with Wiig as a luxury, emphasizing the effortless chemistry they share. Their comedic synergy translates into their relationship, where their shared sense of humor and love for life create a strong foundation.

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The duo often supports each other’s ventures, whether on-screen or off, proving that their connection is rooted in admiration and trust. Fans admire their ability to balance laughter with authenticity, as they remain an example of how friendships can thrive amidst the chaos of Hollywood.

13- Oprah Winfrey and Gayle King

Oprah Winfrey and Gayle King’s friendship spans over four decades, beginning when they worked together at a Baltimore TV station in the 1970s.

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Their bond grew during a snowstorm when King stayed at Winfrey’s home for the night, leading to a lifelong connection. Both women have spoken openly about their unwavering support for one another, with Winfrey describing King as the sister she never had.

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King, in turn, frequently praises Oprah’s generosity and wisdom. Despite their immense individual successes, they prioritize their friendship, often taking vacations together and celebrating life’s milestones side by side.

Their candid discussions about life, relationships, and career challenges have made their bond relatable and inspiring to audiences worldwide.

14- Lily Tomlin and Jane Fonda

Lily Tomlin and Jane Fonda’s friendship began in the late 1970s while filming 9 to 5 and was rekindled decades later with their Netflix series Grace and Frankie.

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Fonda once said that their friendship is one of the greatest joys of her life, describing Tomlin as a constant source of laughter and insight. Similarly, Tomlin admires Fonda’s intelligence and activism, often praising her courage to stand up for what she believes in.

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The two frequently support one another’s causes and celebrate their milestones together, including advocating for women’s rights and environmental issues.

Their relationship is a testament to the power of deep, enduring connections, showing how shared values and mutual respect can build a lasting friendship.

15- Brad Pitt and George Clooney

Brad Pitt and George Clooney’s friendship took off during the filming of Ocean’s Eleven and its sequels.

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Their playful banter, both on and off set, became one of the highlights of their relationship. Clooney often jokes about Pitt’s good looks, while Pitt admires Clooney’s wit and charisma.

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Beyond their shared sense of humor, the two have a deep respect for each other’s work and personal values, often collaborating on philanthropic projects. Pitt has described Clooney as one of his most dependable friends, while Clooney praises Pitt’s humility and kindness.

Their camaraderie is not only entertaining but also heartening, showcasing how two mega-stars can form a genuine, lasting bond.

16- Sophie Turner & Maisie Williams

Game of Thrones sisters Sophie Turner and Maisie Williams met on the show in 2011. They became best friends in real life. They were just 13 and 12 years old at the time. They grew up together while filming GOT. This is what made their sisterhood strong.

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The girls call each other soulmates and share everything. They even have matching tattoos with the date they got their roles in the show.

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Sophie Turner once said, “My best friend Maisie and I have a very special friendship. It’s different from my other friendships. We wanted to make a movie about a friendship where you’re like soulmates, but also friends. It’s a beautiful bond but can be tough sometimes.”